Sun Protective activity of the hydroalchoholic extracts of two Medicinal Flowers

 

S.B. Patil1*, M. Y. Lende1, V. S. Thakur1, N.S. Naikwade1 and C.S. Magdum2 and  R. D. Bendgude3

1Department of Pharmacology, Appasaheb Birnale College of Pharmacy, South Shivaji Nagar, Sangli Maharashtra, India – 416 416

2Rajarambapu College of Pharmacy, Kasegaon, Sangli, Maharashtra, India

3SVERI’S College of Pharmacy, Pandharpur, Maharashtra, India

*Corresponding author E-mail: sandeep_pharmacology@rediffmail.com

 

ABSTRACT:

Sunscreens are chemicals that provide protection against the adverse effects of solar and in particular UV radiation. In this present study UV absorption ability of flowers evaluated from flowers of Thunburgia alata Linn, Abutilon indicum Linn. Extracts were prepared by maceration with a mixture of distilled water and methanol (1:1). The method is performed by UV spectrophotomety in the range of 200 to 400 nm and results of all the extracts shows effective UV absorption in the given range.

 

KEYWORDS: UV protective, Thunburgia alata Linn, Abutilon indicum Linn, hydroalcoholic.

 


INTRODUCTION:

Sun radiation constantly impacts the earth with approximately 50% visible light (400- 800 nm), 40% infrared radiation (IR) (1300- 1700 nm), and 10% ultraviolet radiation (UV) (10-400 nm). UV is divided conventionally to UV-A (320-400 nm), UV-B (290-320 nm), UVC (100-290 nm), and vacuo UV (10-100 nm). Sunscreens are chemicals that provide protection against the adverse effects of solar and in particular UV radiation. But due to high cost and allergy of marketed sunscreen lotions so the alternative use of herbal drugs are now day’s necessarily1.

 

Abutilon indicum L., (Malvaceae) commonly known as “Atibala” in Sanskrit gives excessive tonic strength. Flowers and leaves were used as local application to boils and ulcers and also as an emollient. Also a stronger diuretic and heart tonic2.  Chemically it contains flavonoids (quercetin), saponins, alkaloids and phenolic compounds3.

Thunbergia alata L or black-eyed susan, is well known as a fast-growing, long-flowering, friendly creeper. Medicinally it is used for skin problems, cellulitis, back and joint pains, eye inflammation, piles and rectal cancer. Some people can get contact dermatitis from it4.

 

EXPERIMENTAL:

Plants:

Thunburgia alata L, Abutilon indicum L., flowers were freshly obtained from local region at Sangli. Botanical identification was performed at the Department of Botany by approved botanist at Padmbhushan Dr. Vasantdada Patil Mahavidyalay, Tasgaon, Dist Sangli, Maharashtra, India.

 

Preparation of Extract:

Later the petals were separated and dried. 100 g powdered petals were extracted with Distilled water: methanol (1:1) by maceration. The extracts were evaporated to dryness. Yield was obtained 1.8 gm, 1.7 gm respectively.

 

The general flavonoids identification test was performed on all the four extracts5.

 

Test 1 (Shinoda test): To dry extract, add 5 ml 95% ethanol, few drops concentrated hydrochloric acid and 0.5 g magnesium turnings. Pink colour observed.

 

Test 2: To small quantity of extract, add lead acetate solution, yellow coloured precipitate is formed.

 

Preparation of sample:

Samples were prepared in 8 mg % w/v concentration by using distilled water (8 mg / 100 ml).UV absorption spectra for all the two extracts were obtained in the range of 200-400 nm using Jasco UV spectrophotometer.

 

Following graphs indicates absorption spectra for all the 2 extracts in the given range.

 

Scanning spectra of extracts on UV-spectrophotometer.

 

Figure 1:  indicates the spectrum obtained from Hydro-alcholic extract of Thunburgia alata Linn.

 

Figure 2:  indicated the spectrum obtained from Hydro-alcholic extract of Abutilon indicum Linn.

 

RESULT AND DISCUSSION:

In this study, two plants studied, both plants had sun protective activity by absorbing UV C rays which damage to the skin and hence both extract of flower proved its UV protection ability. Both extract showed a prominent absorbance at 200 – 230 nm. Phytochemical investigation indicated the presence of flavonoids in both extracts and this protection ability may observe due to the presence of flavonoids.

 

REFERENCES:

1.       Payam Khazaeli  and Mitra Mehrabani, Screening of Sun Protective Activity of the Ethyl Acetate Extracts of Some Medicinal Plants, Iranian Journal of Pharmaceutical Research 7 (1);2008: 5-9

2.       Kirtikar KR., Basu BD. Indian Medicinal Plants. 2nded. Vol.2, Allahabad, I: Lalit Mohan Basu, 1961. P.314-315.

3.       Gaind KN., Chopra KS., Phytochemical investigation of Abutilon indicum, Planta Med., 30(2); 1976: 174-88.

4.       (http://www.plantzafrica.com/planttuv/thunbergalata.htm)

5.       Khandelwal KR  Practical Pharmacognosy, 12th Edition, Nirali Prakashan, Pune. 2004 pp. 153.

 

 

Received on 23.12.2012       Accepted on 08.01.2012     

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Asian J. Pharm. Res. 2(1): Jan.-Mar. 2012; Page 37-38